A comprehensive study by Hollenbach et al., which included HLA class II typing results from 820 JIA patients, found that HLA-DRB1*08 is associated with the polyarticular course of JIA in children over six, while HLA-DRB1*11 is linked to the polyarticular form in younger patients and the oligoarticular form. The gene discussed is HLA-DRB1; the disease is juvenile idiopathic arthritis.