The exosomal circ0000284 in cholangiocarcinoma [79], exo-circNRIP1, exo-circNEK9, exo-circNHSL1 in GC [52, 104, 105], exo-circLONP2, exo-circ-ABCC1, exo-circIFT80 in CRC [54, 56, 57], exo-circANTXR1 in HCC [106], also have been reported their metastatic ability. The gene discussed is ABCC1; the disease is hepatocellular carcinoma.