Other higher exo-circRNAs such as exo-circFBLIM1 [164] in HCC, exo-circRanGAP1[53], exo-circNRIP1 in GC[52], exo-circLONP2 [54], exo-circ-ABCC1 [56], exo-circRHOBTB3 [165] in CRC, exo-circ-PDE8A, exo-circ-IARS [26,56] in PDAC also have the potential to become new target for tumor therapy. This evidence concerns the gene ABCC1 and hepatocellular carcinoma.