In fact, some of the most abundant and highly DE genes (normalized counts ≥ 700, log2FC ≥ 2) in the Tpi+ group included components of the Immune Deficiency (Imd) pathway, mucins, serine proteases, and redox balance associated proteins (Fig. 2B, Fig. S3B). The gene discussed is TPI1; the disease is Immunodeficiency.