These conditions encompass a range of disorders including Parkinson’s disease (PD), Alzheimer’s disease (AD), tauopathies, amyotrophic lateral sclerosis (ALS), and polyglutamine (polyQ) expansion disorders such as Huntington’s disease (HD) and various spinocerebellar ataxias (SCAs) such as SCA3 [1]. This evidence concerns the gene ATXN3 and Alzheimer disease.