As can be inferred, AKT defines the consequential cell behavior under a diversity of stimuli, or furthermore, under specific environments as the result of constant multiple stimuli, such as obesity, which is defined by a perennial excess of nutrients, persistently triggering downstream pathways linked to the presence of specific hormones like insulin or highly available intracellular nutrients. Here, AKT1 is linked to obesity due to melanocortin 4 receptor deficiency.