Asthmatic mice with and without fluconazole exhibited retardation of weight gain (Fig. 1B), increased IgE and IL-4 in serum (Figs. 1C and 1D), increased serum IL-6 but not serum TNF-α (increased serum IL-10 only in asthma with fluconazole) (Figs. 1E–1G), and prominent IL-4 and IgE in the lung homogenates (Figs. 1H and 1I). Here, IGHE is linked to asthma.