CDH13 was notably a top upregulated gene obtained from the linear modeling of hepatocellular carcinoma (only after GABRD and PLVAP) in an earlier analysis (Sarathi & Palaniappan, 2019); these observations point to a consistent role for members of the cadherin gene family in cancer progression in gastrointestinal cancers. The gene discussed is GABRD; the disease is hepatocellular carcinoma.