Overexpression of mucin 1 (MUC1) can promote cancer cell proliferation by regulating cell metabolism, and tumor-related MUC1 exhibiting loss of apical localization and aberrant glycosylation in kidney cancer, especially in renal cell carcinoma (RCC) (Milella et al., 2024). This evidence concerns the gene MUC1 and hereditary clear cell renal cell carcinoma.