However, results ofmultivariable analyses found that despite this insignificance lingered afteradjusting for age, gender, interaction of neutrophil/lymphocyte ratio and tertileof visceral adiposity index as well as body mass index, further adjustment ofeither cardiometabolic diseases (hyperlipidemia, hypertension and diabetes) orcardiometabolic diseases + glycohemoglobin + C-reactive protein attained resultsindicating that current smoking was significantly associated with severe CAC,with OR stood at 3.20 and 3.97 respectively [13]. The gene discussed is CRP; the disease is hypertensive disorder.