First of all, we investigated the cancer specificity of certain gene-protein pairs by checking the cell line database in The Human Protein Atlas (HPA), focusing on the following associations: “AVP->AVPR1B,” “CALCA->CALCRL,” “CCL7->ACKR4,” “CLEC11A->ITGA11,” “CXCL12->ITGA4,” “HGF->MET,” “ICAM4->ITGA4,” “IL2->IL2RA,” “NCAM1->ROBO3,” and “NLGN1->NRXN2”. This evidence concerns the gene ACKR4 and cancer.