BDNF and fleck corneal dystrophy: In the context of cerebral hypometabolism in this study we have identified that DNA hypermethylation of GLUT1 (SLC2A1) and key glucose regulatory genes, including MTOR, BDNF, VEGFα and MCT2 (SLC16A7) distinguishes FCDIIa/b from other FCD-subtypes (mMCD, MOGHE and non-lesional) in brain samples.