Per 1-unit mRSS change, the histological parameters with significant associated changes (OR, p-value) were: telangiectasia = 2.01 (p = 0.001); perivascular CD3 + lymphocytes = 1.14 (p = 0.015); and % of CD8 + among CD3 + cell = 1.03 (p = 0.031). This evidence concerns the gene CD8A and telangiectasis.