RORC and infection: Digoxin pretreatment of SFB-colonized Rorγ−/− mice45 did not result in reduced SFB levels or increased susceptibility to infection (Fig. 4a, Extended Data Fig. 9a–b), suggesting that 1) digoxin does not directly kill SFB; and 2) digoxin reduces SFB levels in a RORγt-dependent manner.