INS and obesity due to melanocortin 4 receptor deficiency: Table 4 displays the top 20 keywords, each occurring more than 27 times, highlighting the prominent research focuses. The most frequently appearing keyword was “weight loss” (n = 131), followed by “obesity” (n = 127), “insulin-resistance” (n = 108), “ketone-bodies” (n = 62), “beta-hydroxybutyrate” (n = 56), and “metabolism” (n = 56).