Furthermore, an analysis utilizing the TSIDB database uncovered a significant correlation between AEG-1 and several key factors, including the tumor-promoting cell Th2, immune activator IL6, CXCR4, immunosuppressants CTLA4, IL1, IDO1, LAG3, PDCD1, TGFB1, and the DHC molecule HLA-DPA1. Here, CTLA4 is linked to neoplasm.