The results indicated that AEG-1 was highly expressed in Breast invasive carcinoma (BRCA), Cholangio carcinoma (CHOL), Colon adenocarcinoma (COAD), Esophageal carcinoma (ESCA), HNSC, Kidney Renal Clear Cell Carcinoma (KIRC), Liver hepatocellular carcinoma (LIHC), Lung adenocarcinoma (LUAD), Lung squamous cell carcinoma (LUSC), Rectum adenocarcinoma (READ), and Stomach adenocarcinoma (STAD), and exhibited low expression in Thyroid carcinoma (THCA) and Uterine Corpus Endometrial Carcinoma (UCEC) (Figure 1A). The gene discussed is MTDH; the disease is rectum adenocarcinoma.