IL2 and lupus erythematosus: Low-dose IL-2 increased the number of Treg (36, 38), and restored the T follicular regulatory (Tfr)/T follicular helper (Tfh) cell balance (12) in parallel with the reduction of prednisone use (36, 38) and disease activity (Safety of Estrogens in Lupus Erythematosus National Assessment [SELENA]-SLEDAI) (12).