CASP1 and diabetes mellitus: Diabetes is considered accelerated aging (Shapiro et al., 2023; Bahour et al., 2021; Antal et al., 2022) and aging is promoted by increased inflammatory events such as the activation of caspase-1 (Baechle et al., 2023; Ferrucci and Fabbri, 2018; Li et al., 2023).