For example, gallstone patients had higher levels of IL‐6, IL‐10 and IL‐12p70 than population‐based controls,9 and GBC patients had increased levels of C‐reactive protein (CRP), CCL20, IL‐16, sTNFRI and sTNFRII compared to gallstones controls.10, 11. The gene discussed is CRP; the disease is gallstones.