CTLA4 and neoplasm: One study developed DSF/MS-Cu-2 nanoparticles, and the combination treatment using DSF/MS-Cu-2 and anti-CTLA-4 antibody significantly inhibited tumor growth, and the inhibition of tumor growth was more pronounced in the combination treatment group compared to the group using DSF/MS-Cu-2 or anti-CTLA-4 antibody alone [237].