FDX1 and nonpapillary renal cell carcinoma: In addition, FDX1 is positively correlated with the immune-related gene CD274, and studies have also found that low expression of FDX1 was associated with progression, poor prognosis, and dysregulated immune cell infiltration in ccRCC [92], and high expression of FDX1 was associated with a better prognosis in COAD patients [93].