In this context, we have recently demonstrated that activation of fibroblast growth factor (FGF) signaling is involved in the stabilization of c-Myc oncoprotein in MM cells, strongly supporting the existence of an FGF/FGFR/c-Myc axis that may play a pivotal role in the progression of this hematologic disease [19]. This evidence concerns the gene MYC and Miyoshi myopathy.