MYC and neoplasm: The presence of a link between the FGF/FGFR system and c-Myc, and its correlation with tumor establishment and progression has been suggested since 2010 when it was demonstrated that FGFR3 cooperates with MYC in double transgenic (TG) mice to cause B lymphomas occurring with a higher penetrance and shorter latency than in single TG MYC mice [124, 125].