An age-specific gene expression study of breast cancer in Middle Eastern women identified 63 genes that were specific to YBC ( ≤ 45 years) and 2 genes (TIAM1 and VANGL2) whose expression was significantly lower in breast tumors of very young ( ≤ 35 years) women than in breast tumors from other age groups11. The gene discussed is TIAM1; the disease is breast neoplasm.