It has also been proposed that the levels of the soluble form of LOX-1 (sLOX-1), a consequence of the proteolytic action of ADAM10 proteases on cell bound LOX-1, could be used as a candidate for earlier diagnosis and to provide risk estimates of cardiovascular disease development (Mentrup et al, 2019; Hofmann et al, 2020; Inoue et al, 2010; Li et al, 2018; Yokota et al, 2016). Here, OLR1 is linked to cardiovascular disorder.