TGFB2 and pulmonary fibrosis: demonstrated that TGFβ2 is highly expressed in the lungs of idiopathic pulmonary fibrosis (IPF) patients owing to its lower activation threshold than that of TGFβ1, elucidating a distinct role of TGFβ2 in the progression of IPF.[37] This aligns with our hypothesis that, under estrogen‐deficient conditions, TGFβ2 upregulation precedes that of TGFβ1 to mediate initial responses as the starting point for the fibrotic cascade in the SG.