For instance, excessive TGFβ activation is observed in the SGs of patients with radiotherapy‐induced xerostomia[31] or Sjögren's syndrome,[32] while both duct ligation and exposure to irradiation induce ectopic TGFβ expression in the murine SG.[33, 34, 35] Based on our data, OVX markedly increases TGFβ2 expression in the SG relative to other isoforms. This evidence concerns the gene TGFB1 and xerostomia.