APOE and atherosclerosis: En face oil red O staining of aortas also showed a similar atherosclerosis burden in Apoe−/−LmnaLCS/LCSCdh5‐CreERT2 mice and Apoe−/−LmnaLCS/LCS controls (Figure 6e), and histological analysis of the aortic valves showed indistinguishable lesion area and percentage of perimeter affected by atherosclerosis in the two genotypes (Figure 6f).