PPARA and cancer: As shown in Figure 6a,b, the top three signaling pathways between control and DSS groups are cytokine–cytokine receptor interaction, NOD‐like receptor signaling pathway, and transcriptional misregulation in cancer; the top three signaling pathways between HFD + DSS and DSS groups are PPAR signaling pathway, neuroactive ligand–receptor interaction, and AMPK signaling pathway.