Its backbone chain consists of →4)‐α‐D‐Glcp‐(1→, →3,4)‐α‐D‐Glcp‐(1→ units, with terminal residues of α‐D‐Glcp. Bioactivity evaluations indicated that CSPsN‐1 significantly enhances glucose consumption and ameliorates PA‐induced insulin resistance in HepG2 cells by activating the PI3K/AKT/GLUT4 signaling pathway. Here, AKT1 is linked to Insulin resistance.