Subsequent investigations have identified vascular endothelial growth factor receptor 1 (Flt1) as the primary functional target of miR-200c in endothelial cells, and Flt1 depletion can effectively replicate the anti-fibrotic effects of miR-200c on pulmonary fibrosis (Volpe et al., 2023). The gene discussed is FLT1; the disease is pulmonary fibrosis.