Another molecule, miR-30a, has been shown to attenuate lung fibrosis state in BLM-treated mice by reducing hydroxyproline (HYP), α-SMA, and vimentin expressions while increasing E-cadherin levels, which may be related to its regulation on hydroxymethylation at dynamin-related protein-1 (Drp-1) promoter region, thus inhibiting ten-eleven translocation 1 (TET1, an enzyme converting 5-methylcytosine into 5-hydroxymethylcytosine) expression (Zhang et al., 2017). This evidence concerns the gene ACTA1 and pulmonary fibrosis.