DNASE1L3 and hepatocellular carcinoma: To elucidate the role of DNASE1L3 in HCC, we categorized RNA-seq raw data from 424 liver hepatocellular carcinoma (LIHC) samples obtained from the TCGA database into two groups: the top 100 samples with high DNASE1L3 expression and the top 100 samples with low DNASE1L3 expression (Figure S1E-G).