Furthermore, NCAPD3 accelerates the progression of diffuse large B-cell lymphoma by recognizing H3K9 monomethylation (H3K9me1) on the SIRT1 promoter, which is connected to the SIRT1 promoter by TFII I, and increasing SIRT1 transcription 40. Here, SIRT1 is linked to diffuse large B-cell lymphoma.