QKI and schizophrenia: Haroutunian and colleagues found reduced QKI mRNA expression in Brodmann areas 44, 46, 23, 32, 22, 36, 7, and the hippocampus in SCZ patients, suggesting that aberrant QKI expression might lead to schizophrenia by inducing anomalies in oligodendrocyte and subsequent myelin-associated gene expression (Haroutunian et al., 2006).