AMH = anti-Mullerian hormone; BMI = body mass index; CRP = C-reactive protein; FSH = follicle stimulating hormone; HOMA-IR = homeostatic model assessment for insulin resistance; LH = luteinizing hormone; NO = nitric oxide; PCOS = polycystic ovarian syndrome; QoL = quality of life. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.