In 2013, Dasouki et al. first reported the relationship between THPO and congenital amegakaryocytic thrombocytopenia in a Micronesian family having autosomal recessive R17C THPO mutation with aplastic anemia in a homozygous state and mild thrombocytopenia in a heterozygous state [6]. The gene discussed is THPO; the disease is idiopathic aplastic anemia.