Furthermore, vaccination with the murine ErbB3-ECD-based vaccine candidate inhibited 3LL-R3 tumor progression in an experimental metastasis setting, as fewer metastases were observed in the lungs of vaccinated mice compared to untreated controls (Figure 1E), resulting in lower lung weight (0.33 g ± 0.03 g vs. 0.65 g ± 0.06 g, p < 0.0001) (Figure 1F). The gene discussed is ERBB3; the disease is neoplasm.