Therefore, the use of the PPAR-RXR signaling pathway agonist Dendrobium officinale enhanced fatty acid β-oxidation and ameliorated hepatocyte steatosis (Kamata et al., 2024), Furthermore, in a mouse model of diabetes, combined VDR and RXR agonists were more effective than monotherapy in controlling atheromatous plaques. Here, PPARA is linked to diabetes mellitus.