Moreover, it was reported that lycopene reduced H pylori–associated gastric cancer by decreasing the levels of ROS, inhibiting Jak1/Stat3 activation, eliciting alteration in Wnt/β-catenin multiprotein complex molecules, reducing the expression of c-myc and cyclin E, and decreasing the cell proliferation in H pylori–infected gastric epithelial cells (Park et al., 2019). This evidence concerns the gene STAT3 and gastric cancer.