CD40LG and systemic lupus erythematosus: The authors reported that whole-blood samples from SLE patients with high IFNGS expression were enriched with several inflammation-associated signaling markers, such as CD40L, CXC cytokines, TLR8-mediated monocyte activation, major histocompatibility complex class I, and the plasma cell gene expression signature, compared with patients with low IFNGS expression (38).