Finally, 12 characteristic genes related to the prognosis of ovarian cancer were identified based on the minimum AIC value (2262.89), such as RPL23, PKM2, MRPS12, NDUFC2, HPDL, MRPL14, COA6, FGFR1OP2, RNF144B, CAPN10, ALDH1L1, and ACSM1. Here, PKM is linked to ovarian cancer.