The selective degradation of solid protein aggregates by CCT2 has important implications for the treatment of diseases characterized by the accumulation of insoluble protein deposits, such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease (Erkkinen et al., 2018; Fernández-Ruiz et al., 2015; Sujkowski et al., 2022). This evidence concerns the gene CCT2 and Alzheimer disease.