There are many studies relating to thyroid hormone levels to cognitive function after stroke (Gkantzios et al., 2023; Lei et al., 2019; Li et al., 2021; Murolo et al., 2022), and it has been concluded that the majority of patients with post-stroke cognitive dysfunction have abnormal thyroid hormone levels, and that persistent low thyroid hormone levels exacerbate the dysfunction of the PSCI. This evidence concerns the gene TG and stroke disorder.