PTTG2 and breast cancer: PTTG2 has been implicated in glioblastoma tumorigenesis as well as in head and neck squamous cell carcinoma [36, 48], UTS2 has been reported to possess prognostic value in colorectal and breast cancers [49, 50], TRAT1 in early breast cancer prognosis [51] and DUSP1 in sarcoma progression [35, 52].