Excellent examplesof using ICP-MS in theranostic cancer researchare the studies on DOTA-PSMA-617, both for in vitro and in vivo assays.8−10 DOTA-PSMA-617 is composedof a prostate-specific membrane antigen (PSMA) as the pharmacophoreand a DOTA chelator for binding the metal payload (Figure 2). The gene discussed is FOLH1; the disease is cancer.