Interestingly, in a recent study that quantified SST mRNA levels selectively in layers 2-superficial 3 and deep layers 6-superficial white matter of the DLPFC (Dienel et al., 2023a), the deficit in SST mRNA levels was greater in SZ than in MD; in concert with the present study, these findings suggest that the deficit in SST mRNA levels in other cortical layers may be greater in MD than in SZ. This evidence concerns the gene SST and Menkes disease.