Additionally, it is essential for maintaining the methylation homeostasis of the genome, which is vital to achieving epigenetic regulation.[13] TET1 displays considerable heterogeneity across different tumor types, exhibiting oncogenic or tumor‐suppressive functions.[14] Although numerous studies have examined the function of TET1 in CCA, the potential for exploiting the epigenetic capabilities of TET1 to impede CCA progression remains largely uninvestigated territory. The gene discussed is TET1; the disease is neoplasm.