TET1 and cholangiocarcinoma: Additionally, it is essential for maintaining the methylation homeostasis of the genome, which is vital to achieving epigenetic regulation.[13] TET1 displays considerable heterogeneity across different tumor types, exhibiting oncogenic or tumor‐suppressive functions.[14] Although numerous studies have examined the function of TET1 in CCA, the potential for exploiting the epigenetic capabilities of TET1 to impede CCA progression remains largely uninvestigated territory.