In addition to older age, performance status of 1, low albumin levels, and pathologic stage II or IIIA, multivariable analysis revealed that respiratory sarcopenia was independently associated with increased risk of mortality (hazard ratio, 1.83; 95% CI, 1.15-2.89; P = .01) after adjustment for sex, age, smoking status, performance status, chronic heart disease, FEV1, DLCO, CRP, albumin, CEA, histologic profile, and pathologic stage. This evidence concerns the gene CEACAM5 and sarcopenia.