In addition, MCT4 and Basigin/CD147 have been reported to stimulate vascular endothelial growth factor (VEGF) through the phosphatidylinositol 3 kinase (PI3K) /protein kinase B (Akt) signaling pathway [13], which has been shown to mediate glioblastoma invasion and migration. The gene discussed is BSG; the disease is glioblastoma.