In line with these findings, theincrease in PLIN2 levels infected with WT-VACV was not observed in cellsinfected with vΔVGF (Fig. 7C).Remarkably, PLIN2 levels were rescued by infection with vΔVGF_Rev (Fig. 7C), indicating that VGF is a crucialviral protein required to form lipid droplets. Here, VGF is linked to infection.