IGHV1-2 and diabetes mellitus: They identified seven proteins, including Shbg, Cand1, Apof, Sell, Mia3, Ighv1‐2, and Cfh, as proteomic biomarkers of T2D events.[49] Another study exploring proteomics in peripheral blood and diabetic mellitus type 2 (T2DM) risk incidents also recognized Cfh as a cardinal indicator of T2DM risk.