SERPING1 and Cirrhosis: Univariate analysis revealed that cirrhosis (p = 0.009), serum AFP (p = 0.011), tumor size (p = 0.001), CLIP score (p < 0.001), AJCC stage (p < 0.001), and high SERPING1 levels (p = 0.011) were significant predictors of improved overall survival (Table 2).