Currently, mutations in 13 genes, including NEB (13), ACTA1 (14), TPM3 (15), TPM2 (15), RYR1 (16), TNNT1 (17), CFL2 (18), KBTBD13 (19), KLHL40 (20), KLHL41 (21), LMOD3 (22), MYPD (23), and RYR3 (6), have been shown to cause NM (Table 3). This evidence concerns the gene KLHL40 and nemaline myopathy.