Notably, human A375 melanoma cells produced a similar base level of CXCL10 and CXCL9 (about 200 pg/ml) but in response to IFN-γ, it showed about a 6-fold increase in CXCL10 production, with no increase in CXCL9 production (Supplementary Figure S1E). The gene discussed is CXCL10; the disease is melanoma.