CD4+ T cells from OT-II mice (CXCR3+) engrafted with the ret melanoma cell line transduced to stably express OVA II (ret-OVAII melanoma cell line) were injected into CXCR3KO mice also engrafted with the ret-OVAII melanoma cell line and then treated with CXCL9-Fc, CXCL10-Fc or control IgG1 (Schematic View in Figure 6C, a) and monitored for tumor development. The gene discussed is CXCR3; the disease is melanoma.