Finally, comparative analysis between the spleen and tumor cells of mice treated with either CXCL10-Fc or control IgG (Supplementary Figure S3) showed that successful therapy (Supplementary Figure S3A) led to a significant increase in CD4+ T cells and CD8+ T cells at the tumor site, but not spleen (Supplementary Figure S3B). The gene discussed is CXCL10; the disease is neoplasm.